Hydrogen Inhalation Ameliorates Ventilator-Induced Lung Injury

Source:

http://www.hospimedica.com/critical_care/articles/294732949/hydrogen_inhalation_ameliorates_ventilatorinduced_lung_injury.html

HospiMedica International staff writers

January 13, 2010

A new study has found that inhaled hydrogen gas effectively reduces ventilator-induced lung injury (VILI)-associated inflammatory responses, at both a local and systemic level. 

Researchers at the University of Pittsburgh Medical Center (UPMC; PA, USA), the Taiwanese National Yang-Ming University School of Medicine (Taipei), and other institutions hypothesized that inhaled hydrogen therapy could ameliorate VILI, due to its antioxidant, anti-inflammatory, and antiapoptotic properties. To test the hypothesis, VILI was generated in male mice by performing a tracheostomy and placing the mice on mechanical ventilation (MV).The mice were randomly assigned to treatment groups and subjected to VILI with delivery of either 2% nitrogen or 2% hydrogen in air. Sham animals were given same gas treatments for two hours. The effects of VILI induced by less invasive and longer exposure to MV were also investigated. 

The Latest Asthma Breakthroughs Can Help Your Child

Source:

Victoria Clayton, Special to Lifescript

Published December 25, 2010

http://www.lifescript.com/Health/Conditions/Allergies/How_the_Latest_Asthma_Breakthroughs_Can_Help_Your_Child.aspx?utm_campaign=2010-12-25-68934&utm_source=healthy-advantage&utm_medium=email&utm_content=healthy-well-wise_How%20the%20Latest%20Asthma%20&FromNL=1&sc_date=20101225T000000

Breakthrough: Tylenol (acetaminophen) use linked to asthma.

The research low-down: A large study published this year in the American Journal of Respiratory and Critical Care Medicine found a link between asthma symptoms and acetaminophen use. 

The more acetaminophen children took, the more asthma episodes they experienced, according to the International Study of Asthma and Allergies in Childhood (ISAAC), which looked at 322,959 adolescents in 50 countries.

“In the mid-1970s, we found the link between Reye’s syndrome and aspirin use in children,” says Bradley E. Chipps, M.D., an American Academy of Pediatrics spokesman.“Then we all jumped to Tylenol because we were afraid of aspirin. Now it’s time to rethink Tylenol.” 

What to do: Chipps, an allergy and asthma specialist in Sacramento, Calif., now recommends ibuprofen instead of acetaminophen for his young patients.

“While there’s risk associated with taking any kind of medication [even over-the-counter painkillers], ibuprofen sensitivity in adolescents and children is less than 1%,” he says. “I feel better recommending it.”

But talk to your pediatrician, before avoiding acetaminophen products for your children.